Gambler's ruin: a player with a finite bankroll betting against an infinite-bankrolled opponent (the house) will go to zero with probability 1, given enough time, even at fair (50/50) odds.
With unfair odds (house edge), ruin probability is even higher and faster.
With win probability p, lose probability q = 1−p, starting bankroll N, target M (in bet-units), the probability of reaching M before ruin is:
P(reach goal) = (1 − (q/p)ᴺ) / (1 − (q/p)ᴹ) when p ≠ q
P(reach goal) = N / M when p = q = ½
Ruin probability is just 1 minus that. Here N and M are the bankroll and goal measured in bet-units (bankroll ÷ bet).